α‐Actinin‐1 promotes activity of the L‐type Ca 2+ channel Ca v 1.2
نویسندگان
چکیده
منابع مشابه
Single-channel monitoring of reversible L-type Ca(2+) channel Ca(V)α(1)-Ca(V)β subunit interaction.
Voltage-dependent Ca(2+) channels are heteromultimers of Ca(V)α(1) (pore), Ca(V)β- and Ca(V)α(2)δ-subunits. The stoichiometry of this complex, and whether it is dynamically regulated in intact cells, remains controversial. Fortunately, Ca(V)β-isoforms affect gating differentially, and we chose two extremes (Ca(V)β(1a) and Ca(V)β(2b)) regarding single-channel open probability to address this que...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2020
ISSN: 0261-4189,1460-2075
DOI: 10.15252/embj.2019102622